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How Much Do Medications Cost in Spain? A Price Comparison for Tourists and Expats

Medication Prices in Spain vs US and UK: Complete 2026 Price Comparison

The same inhaler that costs $90 in the US sells for €2.50 in a Spanish pharmacy. Here's what you'll actually pay for common medications in Spain — and why the difference is so dramatic.

If you're visiting Spain from the United States, walking into a Spanish pharmacy will feel surreal. Medications that cost $50, $100, or $350 back home are sitting behind the counter for a few euros. No coupon apps. No insurance negotiations. No prior authorisations. You hand over your prescription, the pharmacist dispenses it, and you pay a price that would barely cover a coffee in Manhattan.

This isn't an exaggeration, and it's not a subsidised rate reserved for Spanish citizens. These are the full, unsubsidised, private-pay prices that anyone — tourist, expat, digital nomad — pays at any pharmacy in Spain. No EHIC card required. No residency needed.

If you're coming from the UK, the savings are more nuanced. The NHS prescription charge of £9.90 per item is already reasonable for expensive drugs, but in Spain you'll often pay less than that — sometimes dramatically less — and you won't need a GP appointment to get there.

85–97%
Typical savings on common prescriptions in Spain
compared to US retail prices without insurance

Why Are Medications So Cheap in Spain?

Spain doesn't have cheap medications by accident. The prices are the result of deliberate government policy, and understanding the system explains why a tourist pays the same low price as a resident.

The Spanish government, through the Ministry of Health and the AEMPS (Agencia Española de Medicamentos y Productos Sanitarios), directly negotiates and sets the maximum retail price for every medication sold in the country. Pharmaceutical companies that want their drugs included in Spain's national formulary must accept the price the government offers. This applies to both the subsidised public system and the private retail market.

Several structural factors keep prices low. Spain mandates generic substitution — pharmacists must dispense the cheapest bioequivalent generic unless the prescribing doctor specifically requests otherwise. The country also uses a reference pricing system that benchmarks drug costs against other European markets. And because Spain manufactures a significant proportion of its own generics domestically, the supply chain is shorter and more competitive.

The result: the average prescription dispensed in Spain costs approximately €11.50 at retail. That's not a copay — that's the entire cost of the medication.

Key point for tourists: There are no "tourist prices" in Spain. The price set by the government is the price everyone pays, regardless of nationality, insurance status, or how you got the prescription. A private prescription from a telemedicine consultation is dispensed at the same regulated retail price as a public prescription from a Centro de Salud.

Prescription Drug Prices: Spain vs US vs UK

The tables below compare what you'd actually pay at the pharmacy counter. For Spain, these are private retail prices (receta privada) — the full, unsubsidised cost with no insurance. For the US, these are average retail prices without insurance. For the UK, we list both the NHS prescription charge and estimated private pharmacy prices, since these are two very different numbers.

Antibiotics

Medication 🇪🇸 Spain 🇺🇸 US 🇬🇧 UK
Amoxicillin 500mg21 capsules · standard 7-day course €3–6 $10–30 £9.90 / £8–15
Azithromycin 500mg3 tablets · Z-pack equivalent €3–5 $15–45 £9.90 / £10–20
Fosfomycin 3gSingle-dose sachet · UTI treatment €4–7 $28–106 £9.90 / £12–25
Augmentin 875/125mg12–14 tablets €4–8 $30–65 £9.90 / £12–20

Fosfomycin is a particularly striking example. In Spain, it's the standard first-line treatment for uncomplicated UTIs — a single sachet mixed in water, taken once, infection resolved. The full retail price is under €7. In the United States, the same single-dose treatment (branded as Monurol) can cost over $100 at retail. It's the same molecule, the same dose, the same manufacturer — just a different country.

Respiratory & Asthma

Medication 🇪🇸 Spain 🇺🇸 US 🇬🇧 UK
Salbutamol inhaler100mcg · 200 doses · Ventolin equivalent €2.50–5 $30–90 £9.90 / £14–20
Fluticasone inhalerPreventer inhaler · Flixotide equivalent €5–17 $80–230 £9.90 / £30–50
Budesonide/FormoterolCombination inhaler · Symbicort equivalent €10–30 $250–500 £9.90 / £40–75

Asthma inhalers are where the transatlantic price gap becomes staggering. A basic salbutamol rescue inhaler — the blue one that every asthmatic carries — costs under €3 in most Spanish pharmacies. The same inhaler in the US runs $30 to $90, even after the recent $35 manufacturer price caps that some companies have introduced. For Americans paying out of pocket for combination inhalers like Symbicort or the equivalent, the savings are in the hundreds of dollars per inhaler.

The UK NHS charge of £9.90 makes this less dramatic for British tourists, though it's worth noting that inhalers are prescription-only in the UK. In Spain, salbutamol inhalers have historically been sold over the counter — though enforcement has tightened in recent years and many pharmacies will now ask for a prescription.

Chronic Conditions

Medication 🇪🇸 Spain 🇺🇸 US 🇬🇧 UK
Omeprazole 20mg28 capsules · acid reflux €2.40–4 $15–40 £9.90 / £5–12
Levothyroxine 100mcg50 tablets · thyroid €2–4 $10–30 Free (exempt) / £8–15
Metformin 850mg50 tablets · diabetes €1.50–3 $4–15 Free (exempt) / £5–10
Atorvastatin 20mg28 tablets · cholesterol €3–6 $10–50 £9.90 / £8–15
Amlodipine 5mg30 tablets · blood pressure €2–4 $8–25 £9.90 / £5–10
Propranolol 40mg30 tablets · beta blocker €2–3 $10–25 £9.90 / £5–12

For chronic medications, Spain's prices are remarkably consistent: nearly everything falls in the €2 to €6 range per box. This matters enormously if you're an expat or long-term visitor managing ongoing conditions. A month's worth of thyroid medication, blood pressure pills, cholesterol treatment, and a proton pump inhibitor might cost €12–15 total at a Spanish pharmacy. The same combination in the US, without insurance, could run $60–150.

British travellers should note that thyroid and diabetes medications are exempt from the NHS prescription charge in England — you pay nothing. For these specific conditions, the UK system is actually cheaper than Spain. But for everything else on a standard prescription, Spain's retail prices are typically below the £9.90 NHS charge.

Antivirals & Reproductive Health

Medication 🇪🇸 Spain 🇺🇸 US 🇬🇧 UK
Aciclovir 200mg25 tablets · cold sores / herpes €3–6 $15–40 £9.90 / £20–35
Valaciclovir 500mg10 tablets €8–18 $70–210 £9.90 / £25–50
Oral contraceptive pill1 month supply · combined pill €3–6 $11–50 Free (NHS) / £10–25
Emergency contraceptionLevonorgestrel · morning-after pill €10–18 $30–50 Free (pharmacy) / £25–35

Valaciclovir is another eye-opener. A course of treatment for a cold sore outbreak costs under €18 in Spain. In the US, the same generic medication averages around $7 per tablet — a ten-tablet course costs $70 before coupons, and suppressive therapy of one tablet daily runs over $200 a month. People on long-term antiviral suppression in the US have been known to stock up during trips to Spain. It's that dramatic.

Contraception highlights an interesting difference between the UK and Spain. The NHS provides contraceptive pills free of charge to all women — one of the genuinely excellent features of the British system. In Spain, the pill requires a prescription and costs €3–6 per month at retail, though some autonomous communities partially subsidise it through the public system. Emergency contraception is available without a prescription in Spain (no age restriction) for around €10–18, which is cheaper than the US but more expensive than the UK where it's free from pharmacies.

Other Commonly Needed Medications

Medication 🇪🇸 Spain 🇺🇸 US 🇬🇧 UK
Epinephrine auto-injectorAnapen / EpiPen equivalent €40–50 $150–650 £9.90 / £60–100
Fluconazole 150mgSingle dose · thrush / yeast infection €3–5 $10–30 £9.90 / £10–18
Loperamide 2mg20 capsules · Imodium equivalent €3–5 $5–12 £3–6 (OTC)

The EpiPen comparison alone is worth noting. An American expat in Spain recently documented paying €42.09 for an Anapen (the Spanish-marketed equivalent), where the same auto-injector costs $150 or more in the US with a GoodRx coupon — and could run over $600 at full retail. That's not a government subsidy. That's just what the product costs in a country with functioning drug price regulation.

Over-the-Counter Medication Prices

One thing that catches visitors off guard: in Spain, virtually all medications must be purchased at a pharmacy (farmacia). You cannot buy paracetamol at a supermarket or pick up ibuprofen at a petrol station. This is a legal requirement, not a cultural preference. The trade-off is that pharmacists are highly trained — many hold qualifications comparable to a GP — and they can advise on minor ailments directly.

In late 2025, Spain reduced prices on thousands of over-the-counter medications. Current prices for the essentials:

OTC Medication 🇪🇸 Spain 🇺🇸 US 🇬🇧 UK
Paracetamol 1g20 tablets €1.50–2.00 $5–10 £0.30–2.00
Ibuprofen 400mg20 tablets €2–3.50 $5–12 £0.50–3.00
Aspirin 500mg20 tablets €3.50–5.00 $5–10 £0.50–3.00
Metamizol (Nolotil) 575mg20 capsules · Spain favourite €2.26 Not available Not available

For basic OTC painkillers, the UK is actually the cheapest of the three countries — supermarkets sell generic paracetamol and ibuprofen for pennies. Spain's pharmacy-only rule means you'll pay slightly more for these everyday basics compared to a British supermarket, though the prices are still very low. The US falls somewhere in between.

Nolotil (metamizol) deserves a mention because you'll encounter it everywhere in Spain. It's the most commonly dispensed painkiller in the country — more popular than paracetamol — and it's genuinely effective for pain and fever. It's not available in the US or UK due to a rare but serious side effect (agranulocytosis), but it's been used safely in Spain, Germany, and much of the world for decades. If a Spanish pharmacist recommends it, they're drawing on extensive clinical experience with the drug.

What Affects the Price You Pay

Public vs private prescription

Spain operates a two-tier system. If you have a public prescription (receta del Sistema Nacional de Salud), you pay a copay — typically 0% to 60% of the retail price depending on your income and employment status. Pensioners pay 10% with a monthly cap. Working adults generally pay 40–60%.

As a tourist, you won't have access to the public system. You'll get a private prescription (receta privada), which means you pay the full retail price. But here's the crucial part: the full retail price in Spain is already lower than most copays in the US. That €6 box of amoxicillin isn't a subsidised price — it's the entire cost.

Generic vs brand name

Spanish law requires pharmacists to dispense the cheapest bioequivalent generic unless your doctor specifically writes "no sustituir" (do not substitute) on the prescription. This keeps costs down automatically. The vast majority of medications dispensed in Spain are generics — you'll notice the boxes usually say "EFG" (Equivalente Farmacéutico Genérico), indicating it's a certified generic.

Pharmacy consistency

Unlike the US, where drug prices can vary by 70% between pharmacies in the same postcode, Spanish pharmacy prices are tightly regulated. You might see a difference of a euro or two between pharmacies, but the wild pricing swings familiar to American consumers simply don't exist here. You don't need a coupon app. You don't need to shop around. Walk into any pharmacy — the green cross — and you'll pay roughly the same price.

What's OTC in Spain That Requires a Prescription Elsewhere

Spain's classification of what counts as over-the-counter versus prescription-only doesn't always match other countries. Some medications that are freely available in your home country require a prescription in Spain, and vice versa.

Important for UK visitors: Several medications that are available over the counter in the UK require a prescription in Spain. The most notable are codeine-containing painkillers (co-codamol, Nurofen Plus) and salbutamol inhalers. If you rely on these, bring enough for your trip or be prepared to see a doctor for a prescription.

Medications that are available OTC in Spain but may need a prescription elsewhere include low-dose omeprazole, certain antihistamines, and some topical corticosteroids. Emergency contraception (the morning-after pill) is available over the counter from any pharmacy in Spain without age restriction — no prescription, no consultation, no questions asked.

Conversely, ibuprofen 600mg requires a prescription in Spain (you can get 400mg OTC). And while codeine-paracetamol combinations are available OTC in the UK, anything containing codeine requires a prescription in Spain.

The Hidden Cost: Getting the Prescription

Medication in Spain is cheap. The expensive part, relatively speaking, is seeing a doctor to get the prescription. This is a critical consideration for tourists, because your €4 box of amoxicillin still requires a prescription — and getting one involves a medical consultation.

Your options, ranked from cheapest to most expensive:

Route Cost Speed Language
Public Centro de SaludWalk-in, EHIC/TSE accepted Free–€80 2–6 hours Spanish (usually)
PrescribeMeTelemedicine, English-speaking doctor €15–30 1–24 hours English
Private clinicIn-person appointment €60–150 Same day–next day Varies
Hotel doctor / house callDoctor comes to you €100–250 1–4 hours English (usually)

This is where the real cost calculation happens. If you need a course of antibiotics, the medication itself might be €5. But the consultation to get the prescription could add €15 to €150 on top. Even at the high end, though, the total cost is still a fraction of what you'd pay for an uninsured doctor's visit plus medication in the United States.

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Practical Tips for Buying Medication in Spain

Finding a pharmacy

Pharmacies in Spain are everywhere — identified by a green illuminated cross — and they're independently owned. Chain pharmacies don't exist here; Spanish law requires each pharmacy to be owned and operated by a licensed pharmacist. There's roughly one pharmacy per 2,100 people, which is one of the highest densities in Europe. In any city, you're rarely more than a five-minute walk from one.

24-hour pharmacies (farmacia de guardia)

Every neighbourhood operates a rotating duty pharmacy that stays open 24 hours. If you need medication at 3am, look for the sign posted on the door of any closed pharmacy — it will list the nearest farmacia de guardia and its address. You can also find your nearest 24-hour pharmacy at farmaceuticos.com.

Bring your medication boxes

If you're taking a chronic medication and need a refill, bring the original packaging. Spanish pharmacists can cross-reference international brand names using a comprehensive database. Even if the name is different in Spain — and it often is — the active ingredient and dosage will match. Showing the box saves time and eliminates confusion.

Payment

Spanish pharmacies accept cash and card. There's no minimum purchase for card payments. Contactless payments work at most pharmacies. You'll receive a receipt (ticket) — keep it if you plan to claim the expense on travel insurance.

Language

In tourist areas (Barcelona, Madrid, Malaga, the islands), many pharmacists speak functional English. In smaller towns, basic Spanish helps. In either case, the pharmacist will print a patient information leaflet with your medication, and Google Translate handles most communication gaps. The pharmacist's clinical knowledge is excellent regardless of language — Spanish pharmacy degrees are six years.

Complete Medication Price List: Spain

Below is a comprehensive reference covering practically every medication a tourist or expat is likely to need in Spain. All prices are the full private retail price (precio de venta al público) — what you'll pay at any pharmacy with a valid prescription or over the counter where applicable. Prices reflect early 2026 and include VAT.

How to read this table: The Rx column indicates whether a prescription is required (✓) or if the medication is available over the counter (OTC). Spanish names are included where they commonly differ from English.

Pain Relief & Fever

MedicationTypical dose / packRx?🇪🇸 Price
Paracetamol1g · 20 tabletsOTC€1.50–2.50
Ibuprofen 400mg20 tabletsOTC€2–3.50
Ibuprofen 600mg40 tablets€2–4
Metamizol (Nolotil)575mg · 20 capsulesOTC€2–3
Dexketoprofen (Enantyum)25mg · 20 tabletsOTC€2.50–4
Naproxen 550mg40 tablets€3–6
Aspirin (AAS)500mg · 20 tabletsOTC€3.50–5
Diclofenac 50mg40 tablets€3–5

Antibiotics

MedicationTypical dose / pack🇪🇸 PriceCommon use
Amoxicillin500mg · 21 capsules€3–6Respiratory, ear, dental infections
Amoxicillin/Clavulanic acidAugmentine875/125mg · 12 tablets€4–8Resistant infections, sinusitis
Azithromycin500mg · 3 tablets€3–5Respiratory, chlamydia
Ciprofloxacin500mg · 14 tablets€3–6UTI, traveller's diarrhoea
FosfomycinMonurol3g · single sachet€4–7Uncomplicated UTI
Cephalexin (Cefalexina)500mg · 12 capsules€3–5Skin, soft tissue infections
Nitrofurantoin50mg · 21 capsules€4–7UTI
Trimethoprim/Sulfamethoxazole160/800mg · 20 tablets€2–4UTI, certain respiratory infections
Doxycycline100mg · 10 capsules€3–5Acne, tick bites, respiratory
Metronidazole250mg · 21 tablets€2–5GI infections, dental infections
Clindamycin300mg · 24 capsules€5–9Skin, dental infections (penicillin allergy)

All antibiotics require a prescription in Spain. No exceptions.

Respiratory & Allergy

MedicationTypical dose / packRx?🇪🇸 Price
Salbutamol inhalerVentolin100mcg · 200 doses✓*€2.50–5
Fluticasone inhalerFlixotide, Inalacor250mcg · 120 doses€5–17
Budesonide/FormoterolSymbicort equivalent160/4.5mcg · 120 doses€10–30
Fluticasone/SalmeterolSeretide, Anasma250/50mcg · 60 doses€15–35
Montelukast10mg · 28 tablets€4–8
Cetirizine10mg · 20 tabletsOTC€3–5
Loratadine10mg · 20 tabletsOTC€3–5
Bilastina (Bilaxten)20mg · 20 tabletsOTC€8–12
Fluticasone nasal spray50mcg · 120 doses€5–10

*Salbutamol: technically requires a prescription, though some pharmacies still sell without one.

Gastrointestinal

MedicationTypical dose / packRx?🇪🇸 Price
Omeprazole 20mg28 capsules✓/OTC**€2.40–4
Pantoprazole 20mg28 tablets€3–5
Loperamide (Imodium)2mg · 20 capsulesOTC€3–5
Domperidone (Motilium)10mg · 30 tabletsOTC€3–5
Metoclopramide10mg · 30 tabletsOTC€2–4
Racecadotril (Tiorfan)100mg · 20 capsulesOTC€8–12
Oral rehydration saltsBox of 6–10 sachetsOTC€5–8

**Low-dose omeprazole 10mg is OTC. The 20mg strength technically requires a prescription, though pharmacists commonly sell it without one.

Cardiovascular & Metabolic

MedicationTypical dose / pack🇪🇸 Price
Atorvastatin20mg · 28 tablets€3–6
Simvastatin20mg · 28 tablets€2–4
Amlodipine5mg · 30 tablets€2–4
Ramipril5mg · 28 tablets€2–4
Losartan50mg · 28 tablets€3–5
Enalapril20mg · 28 tablets€2–4
Lisinopril20mg · 28 tablets€2–4
Furosemide40mg · 30 tablets€2–3
Hydrochlorothiazide25mg · 20 tablets€2–3
Bisoprolol5mg · 28 tablets€2–4
Propranolol40mg · 30 tablets€2–3
Metformin850mg · 50 tablets€1.50–3
LevothyroxineEutirox, Levothroid100mcg · 50 tablets€2–4
Aspirin 100mgAdiro (low-dose cardio)100mg · 30 tablets€1.50–3

All cardiovascular and metabolic medications require a prescription.

Antivirals & Antifungals

MedicationTypical dose / packRx?🇪🇸 Price
Aciclovir oral200mg · 25 tablets€3–6
Aciclovir cream5% · 2g tubeOTC€5–8
Valaciclovir500mg · 10 tablets€8–18
Fluconazole150mg · 1 capsule€3–5
Clotrimazole cream1% · 30g tubeOTC€3–5
Clotrimazole vaginal500mg · single doseOTC€5–8

Reproductive Health

MedicationTypical dose / packRx?🇪🇸 Price
Combined oral contraceptiveYasmin, Microgynon, Diane, etc.1 month · 21 tablets€3–6
Progestogen-only pillCerazette equivalent1 month · 28 tablets€5–9
Vaginal ringNuvaRing equivalent1 ring · 1 month€15–20
Emergency contraception (LNG)Norlevo, Postinor1.5mg · single doseOTC€10–14
Emergency contraception (UPA)EllaOne30mg · single doseOTC€16–20

Dermatology & Topicals

MedicationTypical dose / packRx?🇪🇸 Price
Hydrocortisone cream 1%30g tubeOTC€4–7
Betamethasone cream0.1% · 30g€3–6
Fusidic acid cream2% · 15g€4–7
Mupirocin ointment2% · 15g€5–8
Permethrin cream5% · 30g (scabies)€8–14
Adapalene gel0.1% · 30g (acne)€8–14

Eye & Ear

MedicationTypical dose / packRx?🇪🇸 Price
Tobramycin eye dropsTobrex0.3% · 5ml€3–5
Ciprofloxacin eye drops0.3% · 5ml€3–5
Artificial tearsHyaluronic acid · 15mlOTC€5–10
Ciprofloxacin ear dropsCetraxal0.3% · 10ml€4–7

Emergency & Specialty

MedicationTypical dose / packRx?🇪🇸 Price
Epinephrine auto-injectorAnapen / Jext0.3mg · 1 auto-injector€40–50
Prednisolone30mg · 28 tablets€3–5
MethylprednisoloneUrbason16mg · 10 tablets€3–5
Ondansetron4mg · 6 tablets (nausea)€4–8
Sumatriptan50mg · 4 tablets (migraine)€3–6

Travel Health

MedicationTypical dose / packRx?🇪🇸 Price
Dimenhydrinate (Biodramina)Motion sickness50mg · 12 tabletsOTC€5–8
Oral rehydration saltsBox of 6 sachetsOTC€5–8
Sunscreen SPF50200mlOTC€12–25
Betadine (Povidone-iodine)10% · 50mlOTC€4–6
Saline solution30 single-dose vialsOTC€3–5

This list covers the medications tourists and expats most commonly need. Prices for highly specialised drugs (biologics, cancer treatments, HIV antiretrovirals) are also regulated in Spain and significantly cheaper than the US, but fall outside the scope of a travel health guide. If you need information on a specific medication not listed here, any Spanish pharmacist can look up the current regulated retail price in seconds.

Need a prescription for any of these medications?

PrescribeMe provides online consultations with licensed Spanish doctors who can prescribe any appropriate medication on this list. Prescription sent as an e-receta to your phone, redeemable at any Spanish pharmacy.

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From €15 · Licensed Spanish physicians · Valid at any pharmacy

Frequently Asked Questions

Can I buy antibiotics over the counter in Spain?

No. Despite what older forum posts might suggest, Spain enforced stricter prescription requirements for antibiotics starting in 2019. Pharmacies that sell antibiotics without a prescription risk fines of up to €6,000. You need a valid Spanish prescription for any antibiotic.

Can I use my US or UK prescription in Spain?

Not directly. A US prescription has no legal standing in Spain. UK prescriptions from before Brexit were usable under EU cross-border rules — this no longer applies. EU prescriptions from other member states may work, but in practice, Spanish pharmacies often prefer a local prescription for clarity. The simplest route is to get a Spanish prescription, which takes minutes through a telemedicine consultation.

Are these prices only for generics?

The prices in this guide reflect generic medications, which is what you'll be dispensed by default. Brand-name versions exist but rarely cost significantly more in Spain, because the government regulates the prices of both. The exception is a handful of newer patented medications without generic equivalents.

Will my travel insurance reimburse Spanish pharmacy costs?

Most travel insurance policies reimburse prescription medication purchased abroad, provided you have a receipt and a prescription (or evidence of a medical consultation). Keep both. The irony is that insurance companies love claims from Spain — they'll reimburse €20 for a consultation and medication that would have cost hundreds at home.

Can I stock up on medications to bring home?

For personal use, you can typically bring back a reasonable supply (90 days is the general guideline for most countries). You'll need a prescription for prescription medications. Customs regulations vary by country — the US, UK, and EU all allow personal-use quantities. You cannot resell medications purchased in Spain, and you shouldn't bring back controlled substances without appropriate documentation.

Why doesn't the US do this?

This is a policy question, not a medical one, so I'll keep it brief. The fundamental difference is that Spain's government sets drug prices through direct negotiation, while the US, until recently, prohibited Medicare — its largest purchaser — from negotiating prices with pharmaceutical companies. The Inflation Reduction Act of 2022 began changing this for a small number of drugs, but the structural difference remains vast. Spain treats drug pricing as a public health function. The US has historically treated it as a market function. The results speak for themselves.

Rx
PrescribeMe Medical Team
Licensed Physicians · Registered with the Colegio Oficial de Médicos

PrescribeMe is an online medical consultation service staffed by licensed Spanish physicians registered with the Colegio de Médicos. We help English-speaking tourists and expats access prescription medication in Spain without language barriers or unnecessary delays. All medication prices cited in this article reflect real pharmacy retail prices verified in early 2026.

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